Mendel Lectures: Epigenetic Regulation in Development, Aging and Disease States

11. října 2018, 17:00 (Uložit do kalendáře)

Refektář Mendelova muzea, Mendlovo náměstí 157/1

Rudolf Jaenisch, Whitehead Institute for Biomedical Research, MIT, Cambridge

Rudolf Jaenisch is a Professor of Biology at MIT and a founding member of the Whitehead Institute for Biomedical Research. He is a pioneer of transgenic science, in which an animal’s genetic makeup is altered. Jaenisch has focused on creating genetically modified mice to study cancer and neurological diseases.

His current research focuses on the epigenetic regulation of gene expression, which has led to major advances in creating embryonic stem cells and “induced pluripotent stem" (IPS) cells, as well as their therapeutic applications. In 2007, Jaenisch’s laboratory was one of the first three laboratories world-wide to report reprogramming cells taken from a mouse's tail into IPS cells. Jaenisch has since shown therapeutic benefits of IPS cell-based treatment for sickle-cell anemia and Parkinson's disease in mice. Additional research focuses on the epigenetic mechanisms involved in cancer and brain development.

More information 

Mendel Lectures are part of Life Science Seminar Series